Kyaddala II follows the lives of high school old friends who are reunited by their admission to university.

The mysterious Miss Tina finds her true love when she meets Dave a struggling and disabled musician who makes it against all odds, while Shamim's independence from her recent marriage comes at a cost when she decides to defy the odds and take chances on making it on her own.

The series premiered at a black-carpet and a gold and black dress code event at the Kingdom Kampala on 27 September with most of the cast present.

[16][17] Musical artists Kenneth Mugabi, Allan Toniks, Geosteady, Naava Grey accompanied by Kampala Symphony Orchestra (KSO) performed at the event.

[20][21] It was shot on location at Hana International Mixed School in Kampala and stars actors from Nigeria, Kenya and Uganda and aimed at addressing issues affecting all African youths.

[22] Usama Mukwaya joined the series as the producer, Emmanuel Ikubese and Humphrey Nabimanya executive produced the series while Loukman Ali, Alex Ireeta did cinematography and Lloyd Lutara and Allan Manzi joined as writers together with the show creator, Emmanuel Ikubese.