Kyaikhtiyo Wildlife Sanctuary is a protected area in Myanmar, stretching over 156.21 km2 (60.31 sq mi).

[1] It covers evergreen and mixed deciduous forests an elevation of 50–1,090 m (160–3,580 ft) in Kyaikto Township.

It was established in 2001 to conserve the biodiversity around the Kyaiktiyo Pagoda, a famous pilgrimage site in Mon State.

[5] Key wildlife species are leopard (Panthera pardus), serow (Capricornis milneedwardsiiare), red goral (Naemorhedus baileyi).

[2] Sambar deer (Rusa unicolor), Indian muntjac (Muntiacus muntjak), gaur (Bos gaurus), wild boar (Sus scrofa) are also said to occur in the sanctuary.