The show is syndicated in the late drive slot on the KIIS Network following Will & Woody across Australia, and is a station on iHeartRadio.

On 1 November 2013, it was announced the radio show will end on 2Day FM in December 2013 and move to rival station, KIIS 106.5 from January 2014.

[citation needed] In November 2023, Kyle and Jackie O announced that the show would be networked into Melbourne breakfast on KIIS 101.1 replacing Jase & Lauren from January 2024.

During a separate interview, the company's content director also conceded the show was over sexualised and Sandilands has been asked to tone it down.

Channel Seven executives are "concerned" the backlash towards Kyle could affect the reality show, and editors have been ordered to give the pre-filmed season a "PG brush over".

The syndicated show, The Kyle and Jackie O Hour of Power, airs in metro markets from 6 p.m to 7 p.m each weeknight on the KIIS Network in Sydney, Brisbane, Adelaide, Melbourne and Perth, plus in regional areas on a number of FM stations on the Ace Radio and Super Radio networks.

In its history, the Pop Quiz has given away in excess of $1 million, making it Sydney's "richest" cash radio contest.

[18] Host Kyle Sandilands attributes the show's rating success in part to his and Jackie O's tendency to say what they are thinking, "even if [we're] not sure".

[19] After the show commenced in the Sydney breakfast market in January 2005, it needed only 12 months to claim the top spot in the FM ratings.

[21][22][23] This programming change did not perform well; with 140,000 listeners lost in Melbourne's KISS breakfast show compared to the previous year six months in.

[25] In August 2009, Kyle and Jackie O were suspended following a segment in which they put a 14-year-old girl on a lie detector and then asked her about her sexual history.

[27] Despite the suspension and scandal, Kyle and Jackie O maintained their number-one position in the market, and the show actually grew 0.6 percentage points.

[28] In September 2009, Sandilands apologised after making an on-air remark about how actor Magda Szubanski could lose a lot more weight if she had spent time in a concentration camp.

[31] In August 2011, Sandilands faced criticism from the Indian community over comments he made on the show about the cleanliness of the Ganges River.

The ACMA investigation into the show imposed further restrictions on 2DayFM, meaning that the radio station would be in breach if any broadcast made statements to demean women or girls.

[35] Jackie O made the claim in late April, after it was revealed that Foran had checked into a mental health clinic, and had been granted indefinite leave from his club.

Rugby league writer, Danny Weidler responded at the time "The suggestion from Jackie O on Kiis1065 that Kieran Foran's baby boy is not his is false and offensive to all concerned".

[36] The legal demand instructed the show to make a full retraction of the defamatory allegation against Foran and his ex-partner, and issue an unreserved apology.

In September 2024, the show was criticised by the ABC's Media Watch for recording people on the toilet urinating and forcing the presenters to guess who made the noise.