Léon François Comerre (10 October 1850 – 20 February 1916) was a French academic painter, famous for his portraits of beautiful women and Oriental themes.

Comerre was born in Trélon, in the Département du Nord, the son of a schoolteacher.

From an early age he showed an interest in art and became a student of Alphonse Colas at the École des Beaux-Arts in Lille, winning a gold medal in 1867.

From 1868 a grant from the Département du Nord allowed him to continue his studies in Paris at the famous École nationale supérieure des Beaux-Arts in the studio of Alexandre Cabanel.

A catalogue raisonné of Comerre's work was published in 1980 by Les Presses Artistiques, Paris.