Léon Mébiame (1 September 1934 – 18 December 2015) was a Gabonese politician who was the 2nd Prime Minister of Gabon.

From 1975 to 1990, he served as the longest-serving Prime Minister in Gabonese history, at 15 years and 17 days.

[1][2] Under French colonial rule, he became an inspector of federal police in 1956 and was posted in Chad from 6 January 1957 to March 1959.

[5][6] He was appointed as President of the Libreville Chamber of Commerce, Industry, and Mines on 6 November 2008.

[3] Mébiame died at age 81 at a Libreville clinic on the night of 17–18 December 2015.