Then-Colonel Mulamba was Chief of Staff of the Congolese National Army (ANC) from October 1964, until named Prime Minister after the coup d'état led by Joseph-Désiré Mobutu of 25 November 1965.

Born in the Kasaï region in 1930, Mulamba joined the colonial gendarmerie known as the Force Publique in 1949.

He "gained international fame for.. defence of Bukavu and for conducting one of the most decisive battles of the 1964 north-east revolution the Simba rebellion of 1964.

When Kisangani was recaptured from rebel forces in 1964 he was named military governor of the entire northeastern region."

[2] Mulamba was removed from premiership by Mobutu on 26 October 1966, following pressure from army high command.