[4] Lôh-Djiboua Region was created as part of the 2011 reorganisation of the subdivisions of Ivory Coast.

Prior to this, the territory that is now Lôh-Djiboua constituted the majority of the first-level division Sud-Bandama Region, which also included what is now Fresco Department.

At the reorganisation, the territory of Fresco Department was transferred to Bas-Sassandra District and the remainder of Sud-Bandama became the second-level division Lôh-Djiboua.

Lôh-Djiboua was combined with Gôh Region to form the new first-level division Gôh-Djiboua District.

Lôh-Djiboua is currently divided into three departments: Divo, Guitry, and Lakota.