The Lütschine (German pronunciation: [ˈlʏt͡ʃinə]) is a river in the Bernese Oberland region of Switzerland.

The Lütschine proper runs from Zweilütschinen, where its two tribututaries join, to Lake Brienz at Bönigen.

Both branches of the Lütschine include a large number of mountain streams as tributaries.

[1] A story passed on by word of mouth showing friendly banter between villagers that lived on the two rivers is that the people on the Weisse Lütschine said the others "were so dirty it turned the river black" and the villagers on the Schwarze Lütschine claimed the others "never even washed so the other tributary remained perfectly white".

From Wilderswil to Lauterbrunnen and Grindelwald, the banks of the Lütschine are closely followed by the tracks of the Berner Oberland Railway.