After the 1485 Treaty of Leipzig, the town increasingly fell under the Wettin electors of Saxony, until the episcopal lands were finally secularised in 1547; from 1656/57 until 1738 it was held by the secundogeniture of Saxe-Merseburg.

The town was the scene of two famous battles: By 1815 resolution of the Vienna Congress, Lützen fell to the Prussian province of Saxony.

Part of the Soviet occupation zone after World War II, the town belonged to the East German district of Halle from 1952 to 1990.

In 2017 a mass grave with 47 bodies from the Battle of Lützen (1632) were found near the town.

[4] Seats in the town's assembly (Stadtrat) as of 2019 local elections: Media related to Lützen at Wikimedia Commons