Robb Drugstore was a historic pharmacy in the Columbia-Tusculum neighborhood of Cincinnati, Ohio, United States.

Erected in 1860,[1] it was a four-story building,[2] constructed of brick on a stone foundation and topped with a slate roof.

[3] The building was a simple rectangle in its floor plan, although not without embellishments: the roof, which rose to gables on the sides, was crowned by a large central chimney, while the gables were ornamented with machicolations, and the walls were anchored by brick pilasters.

The windows were of plain lintel construction with lugsills on the sides.

Robb Drugstore was listed on the National Register of Historic Places in 1979.