Lesbian, gay, bisexual, transgender, and queer (LGBTQ) people in Guinea-Bissau face legal challenges not experienced by non-LGBTQ residents.

[2] The U.S. Department of State's 2011 Human Rights Report found that, "the law (in 2011) only recognized heterosexual married couples as entitled to larger government housing.

There were no reported violent incidents or other human rights abuses targeting individuals based on their sexual orientation or identity.

There was no official discrimination based on sexual orientation or gender identity in employment or access to education and health care.

Social taboos against homosexuality sometimes restricted freedom to express sexual orientation, yet society was relatively tolerant of consensual same-sex conduct, according to a 2010 study by the Pew Research Center.In 2018, a local NGO director stated that there were some cases of violence targeting people based on their sexual orientation or gender identity and stressed that Guinea-Bissau lacks legal protections for LGBTI people.