The LI Special Brigade (Italian: LI Brigata Speciale) was an infantry brigade of the Royal Italian Army during World War II.

The brigade was formed on 1 February 1942 in Bari and arrived on 1 March 1942 on the island of Crete.

[1] The brigade was assigned to the 51st Infantry Division "Siena", which commanded the Italian contingent of the German-Italian Fortress Crete Command during the Axis occupation of Greece.

[2] The brigade had its headquarter in Kato Chorio [el] and was responsible for the coastal defense of the easternmost part of Crete along the coast between Ierapetra, Kalo Chorio, Sitia, and Palaikastro.

[1] After the Armistice of Cassibile was announced on 8 September 1943 the brigade surrendered to the Germans.