Laâyoune-Sakia El Hamra (Arabic: العيون - الساقية الحمراء, romanized: al-ʿuyūn as-sāqiya l-ḥamrāʾ) is one of the twelve regions of Morocco.

The region as claimed by Morocco covers an area of 140,018 square kilometres (54,061 sq mi)[1] and had a population of 367,758 as of the 2014 Moroccan census.

[3] Laâyoune-Sakia El Hamra borders the region of Guelmim-Oued Noun to the north and Dakhla-Oued Ed-Dahab to the south.

The Moroccan Wall runs through the region and the area to its east is under the control of the Sahrawi Arab Democratic Republic.

[3] On 29 October 2023, the Polisario Front carried out an operation in the Es Semara Province of the region, dropping four explosive projectiles, killing one Moroccan civilian and injuring three.