LaSalle Hotel is a historic hotel building located at South Bend, St. Joseph County, Indiana.

It was built in 1921, and originally housed 223 hotel rooms.

It is a nine-story, Commercial style brick building with terra cotta trim and a wide overhanging cornice.

[3] The LaSalle Hotel was listed on the National Register of Historic Places in 1985.

This article about a property in St. Joseph County, Indiana on the National Register of Historic Places is a stub.