La Gouesnière (French pronunciation: [la ɡwɛnjɛʁ]; Breton: Gouenaer) is a commune in the Ille-et-Vilaine department of Brittany in northwestern France.

Charles de Gaulle, on a trip to Brittany, stopped in the city on 11 September 1960 before joining Saint-Malo.

La Gouesnière is twinned with Saint-Désert wine village, in the heart of the Burgundy vineyard, quoted in the poem of Aragon, The conscript of the hundred villages, written as an act of intellectual Resistance in a clandestine way in the spring of 1943, during the Second World War.

Inhabitants of La Gouesnière are called Gouesnériens in French.