La Guerche-de-Bretagne (French pronunciation: [la ɡɛʁʃ də bʁətaɲ]; Breton: Gwerc'h-Breizh) is a commune in the Ille-et-Vilaine department in Brittany in northwestern France.

The cellist Louis-Marie Pilet (1815–1877) was born in La Guerche-de-Bretagne.

Inhabitants of La Guerche-de-Bretagne are called Guerchais in French.

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