On a series of flashbacks, her life is told, starting with a visit María paid to another famous Argentina faith healer, Pancho Sierra.

Pancho Sierra instructs Madre María to continue his work by helping the poor and praying with the sick.

After her husband's death, Madre María establishes a mission or co-op in La Rioja Street in Buenos Aires.

Maria's defense prevails in the trial, and a cheering crowd receives her in her home, but she faints and shortly after dies.

The final scene shows a solemn funeral procession taking María's casket to the cemetery.