Its pages would subsequently include bylines by Juan Gelman, Miguel Bonasso, Carlos Ulanovsky, Tomás Eloy Martínez, Ernesto Sábato, Pompeyo Camps, Osvaldo Soriano, Ricardo Halac, Enrique Raab, Roberto Cossa, Victoria Walsh, María Esther Giglio, Raúl Vera Ocampo [es], Pablo Urbanyi, Gerardo Fernández, José Agustín Mahieu, Hugo Gambini, Luis Aubele, Bernardo Verbitsky and other noted figures in Argentine journalism and the arts.

The paper was supportive of the Marxist government of President Salvador Allende in neighboring Chile, and was labeled "Enemy Number One" by the subsequent Chilean dictatorship of General Augusto Pinochet.

The publication was, however, generally supportive of the March 1976 coup that toppled President Isabel Perón in Argentina, describing the nation (referring to left-wing violence) as "helpless before the slaughter.

[8] The daily's opposition to the dictatorship intensified, and on January 30, 1977, its circulation was confiscated, as well as the corresponding color magazine insert, on the charge of "offending the Argentine government and military.

[8] Urged to leave the country by friends and family, Timerman refused,[3] and on April 15, he was abducted by a paramilitary group under the orders of Buenos Aires Province Police Chief Ramón Camps; the publishing house was expropriated in November.

David Graiver's widow, Lidia Papaleo, testified in 2010 to having been intimidated by Clarín Group executive Héctor Magnetto, and subsequently tortured by the police, to forfeit further payment in 1977 for her inherited shares in La Opinión and the nation's leading newsprint maker, Papel Prensa.