La Sierra's rivals are Norte Vista and Hillcrest, the other public high schools in Alvord Unified.

In the 2007–2008 school year, approximately 3,200 students attended La Sierra High.

Hillcrest High School opened in fall 2012 to relieve crowding at La Sierra.

In 2005, La Sierra's students met or exceeded the state expectations on the California Standardized Testing and Reporting (STAR) as listed below:[3] All data below reflect the percentage of sophomore, junior and senior students who passed the CAHSEE sections.

La Sierra is a member of the California Interscholastic Federation (CIF) River Valley League along with Hillcrest, Jurupa Valley, Norte Vista, Patriot and Ramona high schools.