La Wantzenau (French pronunciation: [lavãtsəno]; German: Wanzenau) is a commune in the Bas-Rhin department in Grand Est in north-eastern France.

During the Thirty Years' War, in the early 17th century, the town was completely wiped out by Swedish troops.

The town is twinned with Saint-Yrieix-la-Perche in Haute-Vienne because the population of La Wantzenau was evacuated there at the start of the war with Germany in 1939.

It combines the advantages of village life with individual houses while still being part of the CUS with train and bus transportation to the centre of Strasbourg.

There are also several public buildings including a post office, the town hall, the Foyer Culturel, the Jean-Claude Klein sports complex, a football stadium, two pre-schools, a primary school, and a junior highschool.