The series features Uttara in the lead role as Sodhana, a private detective, supported by Sakshi Ranga Rao and Rama Prabha as her assistants.

These assistants often create humorous situations by unintentionally complicating the investigations, adding a lighthearted element to the series.

[8][9] The title track "Lady Detective.. Ammo Yama Active" was received well and was quite popular.

[10][4] Lady Detective was originally broadcast every Thursday between 8:30 to 9:00 PM on ETV from 1996 to 1997.

[5][2] The title song of the serial was parodied in a deleted scene in the 2019 Telugu film Agent Sai Srinivasa Athreya.