She helped finance and guide early Methodism and was the first principal of Trevecca College, Wales, established in 1768 to train Methodist ministers.

With the construction of 64 chapels in England and Wales, plus mission work in colonial America, she is estimated to have spent over £100,000 on these activities, a huge sum when a family of four could live on £31 per year.

'[4] Selina would later provide the Coram with 'financial support for fees, stamp duties, vellum, seals and others expenses [sic] connected with the presentation of the Foundling Hospital Charter for the King's signature.

According to Schlenther, it was Wesley who first attracted her to Methodism, noting a visit to his chapel in Donnington (Wood) in East Shropshire, in which a rare exception to egalitarian principles was made and she was offered a private pew.

Whitefield became her personal chaplain, and, with his assistance, following problems put in her path by the Anglican clergy from whom she had preferred not to separate, she founded the "Countess of Huntingdon's Connexion", a Calvinistic movement within the Methodist church.

In the earlier part of her life Isaac Watts, Mary, Lady Abney, Philip Doddridge, and Augustus Montague Toplady were among her friends.

[8] In 1748, the Countess gave Whitefield a scarf as her chaplain, and in that capacity, he preached in one of her London houses, in Park Street, Westminster, to audiences that included Chesterfield, Walpole and Bolingbroke.

Moved to further the religious revival in a Calvinistic manner compatible with Whitefield's work, she was responsible for founding 64 chapels and contributed to the funding of others, insisting they should all subscribe to the doctrines of the Church of England and use only the Book of Common Prayer.

Following the expulsion of six Methodist students from St Edmund Hall, Oxford in 1768 the Countess founded a ministers' training college at Trefeca (Trevecca) near Talgarth, in Mid Wales, not far from Brecon.

During the mid-1760s, she met and befriended Mohegan preacher Samson Occom, then on a tour of England to raise funds for Indian missions in the colonies.

[14] She became a slave owner herself in 1770 when she inherited Whitefield's overseas estates in Georgia and South Carolina, including the Bethesda Home for Boys.

Alice Membury, appointed schoolmistress in Melbourne, Derbyshire by Lady Elizabeth Hastings, was ejected by the Countess for 'not turning Methodist'.

[17] Selina successfully petitioned George III about the gaiety of Archbishop Cornwallis' establishment, and made a vigorous protest against the anti-Calvinistic minutes of the Wesleyan Conference of 1770, and against relaxing the terms of subscription of 1772.

Obituaries and tributes were written: Horace Walpole described her as the patriarchess of the Methodists, whilst the Roman Catholic, John Henry Newman, commented She devoted herself, her means, her time, her thoughts, to the cause of Christ.

Lady Huntingdon Lane at the Givens Estates in Asheville, North Carolina, a retirement community affiliated with the United Methodist Church.