According to the QS World University Rankings by Subject 2021, Lady Irwin College was ranked in the range of 251-300 for the subject of "Education"[1][2][3] In 1928, the All India Women's Conference began to raise funds for the college.

[4] The college was established under the patronage of Lady Dorothy Irwin, wife of Lord Irwin, Viceroy of India and the Maharanis of Baroda and Bhopal, Sarojini Naidu, Rajkumari Amrit Kaur, Annie Besant, Kamala Devi Chattopadhyay, Margaret Cousins and Sir Ganga Ram Kaula to name a few in 1931.

Till 1950, it was managed by the All India Women's Education Fund Association, after which it got affiliated to the University of Delhi, and honours degree courses were introduced in the college.

During the pre-independence period, along with Lady Dorothy Irwin, Mahatma Gandhi and Rajkumari Amrit Kaur were amongst the other revolutionists who participated in the struggle by the way of emancipation of women.

The teaching learning transactions true to the motto, endeavour to inculcate a sense of knowledge to serve through carefully designed outreach experiences.