Lady Mi was from Qu County (朐縣), Donghai Commandery (東海郡), which is present-day Lianyungang, Jiangsu.

After Tao Qian's death, they supported Liu Bei to be the Governor of Xu Province and joined his side.

When Lü Bu led his forces to seize Xiapi (下邳; present-day Pizhou, Jiangsu), the capital of Xu Province from Zhang Fei.

Some domestic complications must have followed, for we are told Liu Bei made peace with Lü Bu soon afterwards and his family was returned to him.

A poem honored her sacrifice with those lines: The embattled captain had to have his steed; On foot he could not save the little prince.