She has appeared on over 250 covers of such popular magazines as Cosmopolitan, Vogue, Rolling Stone, Elle and Glamour, and has walked runways for designers such as Yves Saint Laurent, Jean-Paul Gaultier, Chanel, Dior, Dolce & Gabbana, Paco Rabanne, Kenzo, Louis Vuitton, Christian Lacroix, Roberto Cavalli, Jacquemus, Ralph Lauren and Vivienne Westwood.

[5][6][7] Casta's modeling career reportedly began when she was discovered by the photographer Frédéric Cresseaux,[8] during a family holiday in her father's native Corsica, at age 15.

[11] She has been featured in Pantene, Guess?, Tommy Hilfiger, Valentino, Givenchy, Ralph Lauren, Cacharel, Lolita Lempicka, Chanel, Dolce and Gabbana, Nina Ricci, Swarovski, Yves Saint Laurent, Louis Vuitton, Roberto Cavalli, Jacquemus, J.

She has appeared on more than 250 magazine covers[citation needed] including Harper's Bazaar,[12] Elle, Marie Claire, Glamour, Cosmopolitan, Vanity Fair, i-D, Rolling Stone and Vogue (Paris, España, Germany, Russia and Turkey).

[15] She also appeared in Sports Illustrated Swimsuit Issue three consecutive times, as well at the Pirelli Calendar 1999 by Herb Ritts, 2000 by Annie Leibovitz and 2019 by Albert Watson.

[17] For Christmas 2011, Peter Lindbergh shot True Love, the very thought of Casta at the summit of Manhattan and between the snowy lions of marble of the New York Public Library for Tiffany & Co.[18] On 10 March 2010, in Paris, she opened the Louis Vuitton fall/winter 2010 fashion show.

[26] Casta became the focus of a controversy[27] when, after being selected to be Marianne, newspapers in Britain and France[28] reported that she had relocated to London where taxes on high earners are lower.

[33][34] On 6 April 2008, Casta demonstrated in a White March of nonviolent protest to ask for the immediate release of Ingrid Betancourt, presidential candidate kidnapped since 2002 by the FARC.