Lagos bat lyssavirus, formerly Lagos bat virus (LBV) is a Lyssavirus of southern and central Africa that causes a rabies-like illness in mammals.

It was first isolated from a fruit bat (Eidolon helvum) from Lagos Island, Nigeria in 1956.

[citation needed] Lagos bat lyssavirus has been isolated from wild and domestic mammals in southern Africa including bats, cats and one dog.

[2] One isolate was detected in France in 1999 when a fruit bat (Rousettus egypticus), which had been displaying signs of aggression, died.

[3] No human cases of Lagos bat lyssavirus infection have been documented.