The Rasina springs from the southern slopes of the Goč mountain, near the village of Rašovka, southwest of the most famous Serbian spa, Vrnjačka Banja.

The river originally flows to the southeast, around the mountains of Željin and Kopaonik, next to the villages of Mitrovo Polje, Bzenica, Pleš, Jablanica, Grčak, Toskići, Budilovina and Milentija.

At this point the river reaches the western side of the Veliki Jastrebac mountain, and makes a wide, elbow turn to the north.

The lower Rasina region is densely populated (villages of Suvaja, Majdevo, Štitare, Grkljane, Šogolj, Šavrane, Gornji Stepoš, Bukovica, Donji Stepoš, Lipovac, Malo Golovode, Donje Golovode), with the administrative center of the Rasina District, Kruševac.

The Rasina drains an area of 990 km2 (380 sq mi),[2] belongs to the Black Sea drainage basin and it is not navigable.