Lake Sharpe is a large reservoir impounded by Big Bend Dam on the Missouri River in central South Dakota, United States.

[4] Big game animals include whitetail and mule deer, elk, bison, coyotes and wild turkeys.

Waterfowl and upland game birds include ducks, geese, pheasants, prairie chickens, and grouse.

The South Dakota Department of Game, Fish, and Parks maintains several recreation areas and boat launching facilities around the lake.

Both tribes lost extensive fertile bottomlands when the government acquired property that would be inundated by the manmade lake.