The city has chemical, armaments, textiles, paper, leather and rubber goods, wire, apparel, oils and lubricants industries, as well as tanneries, vegetable and fruit canneries.

Several technical schools are located in the city, as well as the Eva Perón Medical Center, one of the largest in the Greater Buenos Aires area.

Before the Spanish conquest, the land that now comprises the Partido de Lanús was inhabited by indigenous tribes, including the Pampas and Guarani.

The Guarani people, particularly the "Guaraníes de las Islas" group living in the estuary of the Plata River, had a more sedentary lifestyle.

This initial settlement had a short lifespan and was only permanently established in 1580 when Juan de Garay founded the city for the second time.

The first landowners in the district included Juan Torres de Vera y Aragón, whose property was also known as Estancia del Adelantado.

Since they didn't meet the residency requirement, their lands were later redistributed to various settlers, such as the cove of Juan Ruíz, Giovanna Gomez, and Pedro de Jerez.

The Partido de Lanús officially became independent on January 1, 1945, bearing the number 111 among the districts of the Buenos Aires province, as decreed on September 29, 1944.

Lanús is also home to the prominent "Hospital Interzonal General de Agudos Evita," founded on August 30, 1952, where patients from other suburbs are treated.

Quindimil's long tenure as mayor ended in the elections of October 28, 2007, when he lost to Darío Díaz Pérez of the Frente para la Victoria.