The Land Title Building and Annex is an American early skyscraper located at 100 S Broad Street in Philadelphia, Pennsylvania.

The earlier, northern one of the building's two towers was erected in 1898 and was fifteen stories tall.

It was designed by Chicago-based architect Daniel Burnham, who was an early pioneer in the development of tall buildings.

The southern, 22-story, 331-foot tower, added in 1902, was also designed by Burnham in collaboration with Philadelphia architect Horace Trumbauer; it was built on the site of the former Lafayette Hotel.

A Pennsylvania Historical and Museum Commission historical marker outside the building commemorates Anne Brancato Wood, a state legislator and entrepreneur whose offices were located in the building.