'Southern Wine Route') is a district (Kreis) in the south of Rhineland-Palatinate, Germany.

Neighboring districts are (from west clockwise) Südwestpfalz, Bad Dürkheim, the district-free city Neustadt (Weinstraße), Rhein-Pfalz-Kreis, Germersheim, and the French département Bas-Rhin.

The river Lauter forms part of the boundary with France in the south.

The white bar in the middle symbolizes the Weinstraße, the touristic route which gave the district its name.

The crown in the middle is taken from the coat of arms of the Bad Bergzabern district, symbolizing the Trifels and Annweiler areas.