Series anchor, Anup Soni, suggests the correct measures to avert crimes while narrating real-life stories revolving around harassment, kidnapping, and murder.

[7] The first season was a weekly program airing on Friday nights, hosted by Diwakar Pundir, who later was replaced by Shakti Anand in late 2004.

These were a part of the show and was done with multiple hidden cameras, line produced and directed by Partha Dey in Delhi, Haryana, MP and Punjab.

During the last quarter of 2017, Soni decided to exit the series citing that he wanted to focus on his acting career in films.

[8] The seventh season titled Crime Patrol-48 Hours premiered on 10 July 2023 and aired on Monday-Friday nights.

A spin-off series Crime Patrol Dial 100 premiered on October 26, 2015, aired on Monday–Thursday nights, and was produced by different production companies.

Bhartiya Stree Shakti (Nagpur Wing), a non-governmental organisation, Information and Broadcasting Ministry of India intervened and asked Sony Entertainment Television not to telecast a program about the Delhi gang-rape case.

Sony TV was to air episodes based on Om Prakash Chautala teacher recruitment scam in the show.

[41] Clearance was challenged in Supreme Court and on 6 March 2013, the episodes of this case were again put on hold.

[42] On 3 May 2013, the Supreme Court allowed Sony TV to telecast episodes as the trial was complete and judgment of conviction and sentence are in public domain.

A December 2022 episode about a murder involving an interfaith relationship which bore similarities with the murder of Shraddha Walkar the same year, faced online backlash with calls of boycott of the broadcaster Sony TV, for allegedly changing the religion of the murder-accused to Hindu and the victim to Christian.

Riptide Malhotra of India TV stated, "The popularity of Crime Patrol is quite high and Sony regularly airs on weekends.

"[47] Riptide Malhotra of India TV gave the series 4/5 stars and further stated, "The show is presented in such a way that will not threaten you but will make you conscious enough with that extra punch and appeal.

The Baby Falak Case sequence aired during February 2012 made the series the most watched Hindi GEG program with 6.78 TVR.

[51] Subramanian S Iyer was nominated for Best Screenplay Writer (drama series & soap) of Indian Telly Jury Awards in 2012, while won in 2013.

Charudutt Acharya won Indian Telly Jury Award for Best Dialogue Writer (drama series & soap) in 2013.