[3] Larkin Poe's early years saw the release of several independent extended plays (EPs) and collaborative albums.

In addition to their original music, Larkin Poe released a covers album titled Kindred Spirits in 2020, showcasing their interpretations of songs by various artists.

[4] After self-releasing two independent albums and touring successfully for four years – appearing on Garrison Keillor's A Prairie Home Companion, the Grand Ole Opry, and performing at Bonnaroo Music Festival – the group announced their disbandment in December 2009.

[7] Over the course of 3 years (2010–2013), Larkin Poe self-released 5 independent EPs, 2 collaborative albums, and a live performance DVD.

[citation needed] In March 2014, producer T Bone Burnett tapped the sisters to record harmonies and instrumentation on the New Basement Tapes' album Lost on the River: The New Basement Tapes alongside Marcus Mumford of Mumford & Sons, Elvis Costello, Jim James of My Morning Jacket, Taylor Goldsmith of Dawes, and Rhiannon Giddens.

[13][14] In February 2017, Larkin Poe performed as part of the backing band at the MusiCares tribute to Tom Petty in Los Angeles, accompanying such artists as Jackson Browne and Don Henley of the Eagles.

The album was recorded in Nashville, produced by Rebecca and Megan, and engineered and mixed by Roger Alan Nichols.

Relatively unknown in that part of the world, the duo impressed with their rendition of "When God Closes a Door", and premiered the title track from their next album.

[22] Larkin Poe's fourth studio album Self Made Man was released on June 12, 2020, on Tricki-Woo Records.