The diversity of his interests, and the success with which his books have met, have together earned Gonick the distinction of being "the most well-known and respected of cartoonists who have applied their craft to unravelling the mysteries of science".
Each two-page comic discussed a recent scientific development, often one in interdisciplinary research.
During the 1994-95 academic year, Gonick was a Knight Science Journalism Fellow at MIT.
[5] In 1997, his 14-issue series, Candide in China, published on the World Wide Web, described Chinese inventions.
He drew the satirical, anti-corporate comic Commoners for Common Ground[6] and later explained: Between 2009 and 2011 Gonick drew a humorous webcomic entitled Raw Materials[8] that deals with technology and business matters, especially database administration.