The school is situated north of the small farming community of Palermo, located just south of Oroville.

The 2014–2015 student population was broken down as follows: 4% American Indian, 10% Asian (mostly Hmong), 24% Hispanic, 1% Black, .1% Filipino, and 53% White.

Las Plumas High has maintained a mock trial team since 1993, and has competed at the state level for 14 years.

Some of LPO's biggest consistent rivals include Fairfield High School, Armijo, Golden Valley, and Franklin.

In 1988 the Las Plumas High School Marching Band and Auxiliary represented the United States of America at the World's Fair in Brisbane, Australia under the direction of Glenn and Carolyn Dawson.

The band and auxiliary toured for ten days on the eastern coast of Australia presenting student leadership and marching techniques before performing at the world's fair.

Activities including tailgate parties and movie nights help freshmen to become more involved in high school life.

The Safe School Ambassadors are students trained to identify potential problems on campus dealing with bullying and mistreatment.

About this same time, Steve Green and George Kerth, two members of the class of '65, designed the multi-colored Thunderbird that was used as the school's symbol during its early years.

Student Greg Wright brought a gun to school and held a drama class hostage in the band room.