The airport is about 160 kilometres east of Melbourne, off the Princes Highway, 4 nautical miles (7.4 km; 4.6 mi) west[1] of Traralgon.

The airfield was originally located at Morwell and at Moe before moving to the present site.

[2] The Latrobe Valley Aero Club operates out of Latrobe Regional Airport, providing services to the surrounding community such as Flight Training, Aircraft Rental, Air Charter, Scenic Flights and Air Safari's.

Bandicoot Adventure Flights operate vintage and World War II aircraft including Tiger Moths, a T-6 Texan, and a Pitts Special.

There is also the Latrobe Flying Museum – its fleet consisting of a CAC Sabre, P-51 Mustang, a Commonwealth Aircraft Corporation Winjeel and a Douglas DC-3.