She has written five novels and two short story collections, including Delicate Edible Birds (2009), Fates and Furies (2015), Matrix (2022), and The Vaster Wilds (2023).

[4][5][6] Groff's first novel, The Monsters of Templeton, was published by Hyperion on February 5, 2008, and debuted on The New York Times Best Seller list.

It is interspersed with voices from characters drawn from the town's history as well as James Fenimore Cooper's The Pioneers, which is also set in a fictionalized Cooperstown called Templeton.

Groff's second novel, Arcadia, was released in 2012[12] and tells the story of the first child born in a fictional 1960s commune in upstate New York.

[15] The novel was recognized as one of the Best Books of 2012 by The New York Times,[16] The Washington Post,[17] NPR,[18] Vogue,[19] The Globe and Mail,[20] The Christian Science Monitor,[21] and Kirkus Reviews.

[30][31] The Guardian called Groff's storytelling "a heroic pushback against the way we live now, against waste, against the artificial environments in which we find ourselves maintained by corporations, but equally against the pressures on women to be flawless, effortlessly excellent mothers, wives, sisters, lovers, friends, within this dire state of affairs.

Matrix is about a "seventeen-year-old Marie de France... sent to England to be the new prioress of an impoverished abbey, its nuns on the brink of starvation and beset by disease.