Auzière-Jourdan was born in 1977 to André-Louis Auzière, a banker, and his wife Brigitte (née Trogneux) a teacher.
[3][4] Macron's parents first thought he was interested in Auzière-Jourdan after she remarked that there was a boy in her class who "knows everything about everything".
[6][8] Auzière-Jourdan graduated from Pierre and Marie Curie University (UPMC University of Paris VI) and completed her thesis of exercise, Facteurs échographiques associés à un niveau de BNP élevé chez les insuffisants cardiaques: interaction systole diastole, in 2004.
[9] She has an older brother, Sébastien, an engineer, and a younger sister, Tiphaine, a lawyer.
[2] Auzière-Jourdan practices high-risk cardiology[10] and vascular diseases[6] in Vincennes and Nogent-sur-Marne.