Le Haut-Saint-François (French pronunciation: [lə o sɛ̃ fʁɑ̃swa]; The Upper Saint-François [St. Francis]) is a regional county municipality in southeastern Quebec, Canada in the Estrie region.

Its seat is in Cookshire-Eaton, and it is named for the Saint-François River which runs through the RCM.

There are 14 subdivisions within the RCM:[2]

Mother tongue data, from Canada 2016 Census:[3] Highways and numbered routes that run through the municipality, including external routes that start or finish at the county border:[5]