The district is composed of Ohio, western Pennsylvania, eastern Kentucky, and the northern panhandle of West Virginia.

[1] The bank building is a 13-story 203 foot high-rise, located at Superior Avenue and East 6th Street in downtown Cleveland.

[3] In January 2006, the bank opened the Learning Center and Money Museum, replacing the public teller windows vacated after September 11, 2001.

Over 30 hands-on exhibits focus on the history of money, its effects on societies and cultures, and its central role in peoples' lives.

The museum includes a variety of activities and multi-media experiences to educate visitors, including computerized games about trading, writing contests, crayon rubbings, videos, speeches, films, and virtual tours,[5] One recent addition to the Learning Center and Money Museum is the documentary titled "The Panic of 1907" which details how the panic led to the creation of the Federal Reserve System.