[4] Lee Hyun-wook started his acting career playing in short films: Repatriation (2000), The Camel (2008), Thorn Hearted (2010) and The Out Boxer (2011).

[7] In 2014, Lee made his television debut in the action-thriller series Three Days as the right-hand man of Choi Won-young's character.

[11] In 2015, Lee made his theater debut in True West, playing the main character Austin.

[22][23] Later that year, he made a guest appearance in the tenth episode of Pegasus Market which stars his close friend Lee Dong-hwi.

He also starred in the highly anticipated tvN drama Mine as the husband of actress Lee Bo-young's character.

[30] At the 58th Baeksang Arts Awards, Lee was nominated for Best Supporting Actor in a Korean drama for his role as Han Ji-yong in Mine.