[3] Her mainstream debut was in 2015, with both crime film Coin Locker Girl as pink-haired rogue girl living in Incheon's Chinatown[4] and tvN's romantic comedy television series Hogu's Love as the protagonist's twin sister.

[5] In 2017, Lee received critical acclaim for two films: a romantic coming-of-age about a schoolgirl who falls for her coach Yongsoon in which Lee got nominated for several major film awards,[6] and a crime legal Heart Blackened in which her role as a murder suspect daughter of a powerful businessman earned her the first win and youngest winner record of Baeksang Arts Awards for Best Supporting Actress.

[7][8] Lee returned to small screen with 2018 SBS workplace drama Where Stars Land, as the youngest team member of Incheon International Airport's Security Service.

She acted as a cold and heavily-pressured law school student in JTBC's legal crime Law School,[10] and as a tough firstborn daughter of the family main cast in the film that brings a second Baeksang Arts Awards for Lee 4 years after her first win, docudrama Miracle: Letters to the President.

[11][12] In 2022, Lee acted in tvN's crime mystery Adamas as a TV reporter who hides a secret of being a murder witness in her childhood.