Major General Adam Stephen established a hunting lodge “The Bower” in 1750 one mile west of Leetown along Opequon Creek.

Their mutual Revolutionary War colleague General Horatio Gates, the victor of the Battle of Saratoga, lived four miles north of town in the estate "Traveler’s Rest".

It was consecrated in 1846 as part of the recovery of the Episcopal Church in (then) Virginia after its low ebb in the years after the Revolution.

On July 3, 1864 a running battle took place through the town in which troops under Lieutenant General Jubal Early, after initial setback, prevailed over Federal forces.

After the conflict, the artist David English Henderson resided in Leetown, rendering on canvas his memories as a soldier in the Army of Northern Virginia.