Leipsic is a town in Kent County, Delaware, United States.

The Leipsic River flows through the town on the southern edge of the Bombay Hook National Wildlife Refuge.

About 10.2% of families and 14.9% of the population were below the poverty line, including 20.0% of those under the age of eighteen and none of those sixty-five or over.

Portions south of the Leipsic River are in the Capital School District.

Delaware Route 9, a scenic route running near the Delaware Bay, passes north–south through Leipsic along Denny Street, heading north toward the Bombay Hook National Wildlife Refuge and south toward Little Creek.

Smyrna-Leipsic Road splits northwest from DE 9 north of Leipsic and heads toward Smyrna.