Leipzig Karlsruher Straße (German: Haltepunkt Leipzig Karlsruher Straße) is a railway station located in Leipzig, Germany.

The station opened in June 1983 and was closed between April 2011 and 15 December 2013.

The station is located on the Leipzig-Plagwitz–Leipzig Miltitzer Allee railway.

The train services are operated by Deutsche Bahn, as part of the S-Bahn Mitteldeutschland.