[2][4] Lejeunea drehwaldii is a small, bright green liverwort that grows primarily on the surfaces of living leaves (epiphyllous).

The plant body, or gametophyte, spreads closely against its substrate, reaching 1.5–2.3 mm in width, and displays extensive branching.

A unique feature of this species is the presence of specialized dead, transparent (hyaline) cells forming a border around the leaf edges, which is visible in mature leaves but absent in young ones.

The female reproductive structure (perianth) is cylindrical to egg-shaped and lacks the distinct ridges (keels) found in many related species, instead featuring a unique umbilicate (navel-like) apex formed by a ring of triangular cells.

[5] The spore-producing structure (sporophyte) of L. drehwaldii includes a black, spherical capsule measuring 250–330 micrometres in diameter, which splits into four parts upon maturity.