[4][5] She has also worked as a dance instructor, physical therapist, and account representative for the Chicago Reader.
[3] She was also the director of operations for the 2017 Women's March's Chicago protest, helped found non-partisan voter registration organization ILVOTE, and served on the board of the Andersonville Chamber of Commerce.
[6][4] In July 2022, incumbent 48th ward alderman Harry Osterman announced that he would not run for re-election.
[12] She won the runoff election on April 4, despite Dunne having a fundraising advantage and the endorsement of Osterman.
[14] Manaa-Hoppenworth has said she will join the Progressive Caucus on City Council, and that her initial priorities include "approving ranked-choice voting, homelessness prevention effort Bring Chicago Home and the emergency mental health initiative Treatment Not Trauma.