In January 2023, the company started extensive layoffs[9] (of about 300 of its current employees, or ~5% of the workforce) as a part of major restructuring and reorganization in anticipation of a possibly planned IPO.

[11] In August 2023, it was announced LEO Pharma had entered into a definitive agreement to acquire key assets of the Basking Ridge-headquartered biopharma company, Timber Pharmaceuticals, for $36 million.

[13] In September 2023, the company announced the implementation of a new capital structure with over 4 billion Danish kroner (approximately $587 million) allocated for business development and mergers and acquisitions.

In February 2024, LEO Pharma announced a net loss of 3.6 billion Danish kroner (equivalent to $528 million) for 2023 due to non-recurring project impairments, tax asset adjustments, and rising interest expenses.

The accusation was that LEO Pharma had acted outside the UN system during the first Gulf War by bribing employees in the relief program and thereby helping Saddam Hussein.

In Berlingske Business on June 6, 2015, Gitte Aabo speaks about her personal responsibility and that LEO is ready for a few years of lower earnings, which is a possible consequence of her intervention in employee relations.