He moved on to Allentown Prep, where he lettered in football, basketball, and baseball during the 1919–20 school year.

He then matriculated at The Kiski School in Saltsburg, Pennsylvania in 1921, where he played football alongside Bill Amos and also lettered in basketball and track.

[1] Prendergast attended Lafayette College, where he played football as a tackle under Jock Sutherland in 1922.

[1] He served as the head football coach at Lehigh University, located in Bethlehem, from 1943 to 1945, compiling a record of 3–15–1.

On March 20, 1947, Prendergast resigned his position at Lehigh to take a job as head coach of the Bethlehem Bulldogs of the American Football League.