In 2004, he played the world premiere of Paul Hindemith's Klaviermusik, a piano concerto for the left hand completed in 1923, with the Berlin Philharmonic.

After being treated by neurologist Daniel B. Drachman, he regained some control of his right hand and played and recorded two-hand repertoire again.

At age nine, he became one of the few child prodigies to be accepted for study with the renowned Austrian teacher Artur Schnabel, who taught him in a tradition that descended directly from Beethoven through Carl Czerny and Theodor Leschetizky.

[8] When he was 24, Fleisher became the first American to win a prestigious piano competition established by Queen Elisabeth of Belgium, which helped to catapult his career.

[9] In 1964, at the age of 36, Fleisher lost the use of his right hand, due to a neurological condition that was eventually diagnosed as focal dystonia.

Kennedy Center Chairman Stephen A. Schwarzman described him as "a consummate musician whose career is a moving testament to the life-affirming power of art.

[1] In 2004, Fleisher played the world premiere of Paul Hindemith's Klaviermusik (Piano Concerto for the Left Hand), Op.

On October 2, 2005, Fleisher played the American premiere of the work, with the San Francisco Symphony under Herbert Blomstedt.

[13] In 2012, at the invitation of Justice Ruth Bader Ginsburg, Fleisher performed at the Supreme Court of the United States.

[15][16] His students include Frank Lévy, André Watts, Yefim Bronfman, Hélène Grimaud, Louis Lortie, Dina Koston, Jonathan Biss, Lori Sims Nicholas Angelich, Joel Fan, and Galen Deibler.